Ischemia Reperfusion Injury: Where to Interrupt the Damaging Process
نویسندگان
چکیده
منابع مشابه
Evaluating the Recovery Process of Renal Ischemia/Reperfusion Injury in Rats Using Small-Animal SPECT
Background: Renal injuries associated with ischemia/reperfusion are a prevalent clinical phenomenon that can cause the emergence of progressive kidney diseases, eventually leading to chronic kidney injuries. The present study was conducted to evaluate the results obtained from non-invasive imaging using small-animal SPECT and investigate the recovery process in an animal model of renal ischemia...
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متن کاملIschemia/Reperfusion Injury
This study assessed gentamicin's effects on ischemia/reperfusion renal injury to better understand when and how it worsens postischemic acute renal failure. Rats were subjected to 25 minutes of renal pedicle occlusion with and without preischemic (15-minute) or postischemic (15-minute or 8-hour) gentamicin treatment (100 mg/kg, by itself a subtoxic dose). Gentamicin's impact on hypoxia/reoxygen...
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24 Interferon regulatory factor-1 (IRF1) is a nuclear transcription factor that induces inflammatory 25 cytokine mediators and contributes to hepatic ischemia-reperfusion injury (I/R). Currently, no 26 strategies to mitigate IRF1-mediated liver damage exist. Interferon regulatory factor 2 (IRF2) is a 27 structurally similar endogenous protein that competes with IRF1 for DNA binding sites in IRF...
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ژورنال
عنوان ژورنال: Journal of Transplantation Technologies & Research
سال: 2012
ISSN: 2161-0991
DOI: 10.4172/2161-0991.s3-e001